What is The M367 Pill?

Table of Contents

M367 is a prescription painkiller that combines acetaminophen and hydrocodone bitartrate. Although effective for treating moderate to severe pain, M367 is a controlled substance due to its potential for abuse and addiction.

This brief guide illuminates issues that include:

  • What is M367 pill?
  • What pill has M367 on it?
  • Is hydrocodone M367 addictive?
  • How to connect with treatment for opioid addiction in Ohio.

M367 Overview

What is M367, then? M367 is a pain reliever that blends hydrocodone bitartrate and acetaminophen. It is a white pill with M367 imprinted on one side.

Acetaminophen is a non-opioid medication, whereas hydrocodone bitartrate is an opioid pain reliever. Typically, M367 pills are formulated with a 10mg/325mg ratio, with hydrocodone bitartrate present in a lower quantity. This medication is available exclusively with a supporting prescription.


Hydrocodone bitartrate is an opioid drug that attaches to mu-opioid receptors located in various parts of the central nervous system, such as the gut, nerve cells, spinal column, and brain. By binding to these nerve receptors, hydrocodone bitartrate effectively blocks pain signals, providing relief from injury or disease-induced pain. Additionally, its antitussive properties help suppress involuntary muscle movements that cause coughing. However, excessive suppression of these reflexes can lead to respiratory depression, impairing the efficient exchange of gases like oxygen and carbon dioxide in the lungs.

Acetaminophen tablets, by contrast, are considered safe as they are non-narcotics (non-opioids) that do not lead to habit-forming tendencies or frequent overdosing. Acetaminophen functions by inhibiting the production of prostaglandin in the brain, thereby reducing the sensation of pain. Moreover, it also exhibits a cooling effect on the body, particularly beneficial in lowering fever.


The combination of medications in M367 pills allows the drug to elicit many different effects. As an opioid, hydrocodone serves as both an analgesic, relieving pain, and an antitussive substance, preventing coughing.

Hydrocodone’s mechanism of action involves direct modulation of the respiratory center in the brain stem, effectively suppressing involuntary coughing. Beyond this, it interacts with opioid receptors in the brain, influencing how pain signals are processed.

Acetaminophen, otherwise known as paracetamol, acts as an analgesic and possesses properties that aid in reducing body temperature, making it an effective fever reducer. It is frequently combined with other medications to achieve various therapeutic effects. When it comes to the M367 pill, acetaminophen enhances the ability of hydrocodone bitartrate to address moderate to severe pain.

Potential for Abuse

Acetaminophen is non-addictive and does not lead to the development of tolerance. That said, hydrocodone bitartrate carries a significant risk of abuse due to its opioid properties. Prolonged use or misuse of this drug can lead to mental and physical dependence, often leading to the development of addiction.

When M367 is used appropriately to manage ongoing pain, the likelihood of addiction is low, although some people may experience withdrawal symptoms upon discontinuation.

Addiction typically arises when hydrocodone bitartrate is used in excess of the prescribed dosage or for longer than recommended by a medical professional. Following proper medical guidance and dosage instructions helps minimize the risk of addiction to this medication.

man sitting on a bench representing what is m367

Is M367 a Controlled Substance?

The primary U.S. government agency responsible for combating drug distribution and trafficking is the DEA (Drug Enforcement Administration). In addition to its law enforcement role, the DEA also conducts studies and categorizes various drugs based on their abuse potential.

M367 has been classified by the DEA as a Schedule III controlled substance. Drugs in this category have a moderate to low likelihood of causing physical or psychological dependence. The reason for M367’s placement in Schedule III is due to its hydrocodone content, which is an opioid drug. Other drugs in this schedule include methadone, oxycodone, and hydromorphone.

Substances classified under Schedule III are subject to specific restrictions intended to prevent abuse. While not as stringent as drugs in schedules I and II, the regulations are still firm. Doctors are limited to prescribing only 100 units, and pharmacies cannot dispense more than the prescribed amount. Refills are permitted up to 5 times in a 6-month period, and any M367 prescription becomes void if the drug is not purchased within 180 days from the date of issuance.

M367 Addiction

M367, a combination drug containing hydrocodone bitartrate and acetaminophen, has the potential for addiction due to its opioid component. Addiction to M367 is a serious medical condition that is characterized by a cluster of symptoms, as defined in DSM-5-TR, the most recent revised edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5). These symptoms include:

  1. Taking M367 in larger amounts or for longer than intended.
  2. Unsuccessful attempts to moderate or discontinue use of M367.
  3. Spending lots of time obtaining and using M367 or recovering from its effects.
  4. Cravings to use M367.
  5. Ongoing use of M367 triggering a failure to fulfill personal and professional commitments.
  6. Continuing M367 even though it is causing or inflaming social and interpersonal problems.
  7. Giving up or reducing important activities due to M367 use.
  8. Recurrent M367 use in potentially dangerous situations.
  9. Sustained use of M367 even though it is causing or exacerbating a physical or mental health condition.
  10. Tolerance to M367 developing, meaning that higher doses are required to achieve the initial effects.
  11. Withdrawal symptoms manifesting in the absence of M367.

The development of addiction to M367 can have severe consequences on health, relationships, and overall well-being. Individuals who are addicted to M367 may find it difficult to control their drug use and may continue using the drug despite experiencing negative consequences in various areas of their life.

Overcoming M367 addiction typically requires professional help and support. Treatment may involve a combination of medical detoxification, behavioral therapies, counseling, and participation in support groups. Medical detoxification can help manage withdrawal symptoms in a safe and controlled environment, while behavioral therapies address the underlying issues contributing to addiction and teach coping strategies to prevent relapse.

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Get Treatment for M367 Pill Addiction at Ohio Recovery Centers

Here at Ohio Recovery Centers in Cincinnati, we specialize in treating opioid addictions like M367 addiction.

Studies suggest that most mild and moderate opioid addictions respond just as well to intensive outpatient treatment as inpatient treatment. Outpatient rehab also offers a more flexible, affordable pathway to recovery without compromising the quality of care you receive. Choose from a traditional outpatient program or an IOP (intensive outpatient programs) depending on your circumstances and the severity of your opioid addiction.

Therapy at Ohio Recovery Centers involves a combination of holistic, behavioral, and pharmacological interventions. A robust aftercare component to all treatment programs means that you will leave our facility with relapse prevention techniques, coping strategies, and ongoing outpatient therapy if required.

Call admissions today at 877-679-2132 for immediate assistance fighting opioid addiction.

Table of Contents

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Joseph Gilmore

Joseph Gilmore has been working in the addiction industry for half a decade and has been writing about addiction and substance abuse treatment during that time. He has experience working for facilities all across the country. Connect with Joe on LinkedIn.
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Christopher Glover CDCA

My name is Christopher Glover, and I am from Cincinnati, Ohio. I am currently in school and working to grow in competence to better support our community. As a recovering individual I know the struggles that you or a loved one can go through and that there is help for anything you may be struggling with.

The hardest part is asking for help and we are here as a team to best support you and your decision to start your journey towards a better future. Connect with Chris on LinkedIn

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Amanda Kuchenberg PRS CDCA

I recently joined Ohio Community Health Recovery Centers as a Clinical Case Manager. I am originally from Wisconsin but settled in the Cincinnati area in my early 20s.  My career started in the fashion industry but quickly changed as I searched to find my drive and passion through helping others who struggle with addiction. 

As someone who is also in recovery, I wanted to provide hope, share lived experience, and support others on their journey.  I currently have my Peer Recovery Support Supervision Certification along with my CDCA and plan to continue my education with University of Cincinnati so I can continue to aid in the battle against substance addiction. Connect with Amanda on LinkedIn.

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Patrick McCamley LCDC III

 Patrick McCamley (Clinical Therapist) is a Cincinnati native who has worked in substance use disorder/co-occurring mental health disorder treatment since 2019. Patrick received his bachelors degree in psychology from University of Cincinnati in 2021 and received his LCDC III (Licensed Chemical Dependency Counselor) license from the Ohio Chemical Dependency Professionals Board in 2022. Patrick has worked in Clinical Operations, Clinical Case Management, and Clinical Therapy throughout his career.

Patrick has tremendous empathy and compassion for the recovery community, being in recovery himself since 2018. Patrick is uniquely qualified to be helpful because of the specific combination of his academic background and his own experience in recovery.

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Bill Zimmerman CDCA

Bill Zimmerman is a Greater Cincinnati Area native who has worked in substance use disorder/co-occurring mental health disorder treatment since 2018. Bill received his (Chemical Dependency Counselor Assistant) license from the Ohio Chemical Dependency Professionals Board in 2020.

Bill has worked in Clinical Operations in both support and supervision, and Program facilitating and 12 step recovery support during his career. Bill has a passion for the recovery community, having been in recovery himself since 1982. Connect with Bill on LinkedIn

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Taylor Lilley CDCA, PRS

Growing up in Louisiana with addiction running rampant on both sides of my family. A life away from drugs and alcohol seemed impossible for someone like me. I remember what it was like sitting across from someone thinking there is no way they could ever understand what I was going through.

Sharing my experience offers a credibility and a certain type of trust with clients that only someone who has walked down this road can illustrate. To immerse myself further into the field of addiction, I am currently studying at Cincinnati State for Human and Social Services.  I hope I never forget where I came from, if I can do it, so can you!

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Thomas Hunter LSW

Hello my name is Thomas Hunter. I was born and raised in Cincinnati, Ohio. I am a licensed social worker.In my scope of practice I have worked in the areas of mental health and recovery for thirty years. The clients I have worked with in my career have ranged in age from seven to seventy.

I strive each day to serve my purpose of helping those in need and I believe I do so by utilizing all of my experiences to accomplish my goal of supporting those who desire to establish their sobriety and maintain it in their recovery. Connect with Thomas on LinkedIn.

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Mary D.Porter,LICDC

 My name is Mary D. Porter. I received my Masters of Social Work in 2008 from The University of Cincinnati. I received My Licensed Independent Chemical Dependency Counselor Licensure in 2001. I retired from The Department of Veteran Affairs Medical Center on April 14, 2014. Currently, I am the Associate Clinical Director for The Ohio Community Health Recovery Centers in Cincinnati.. Due to the fourth wave of the Opioid Epidemic in 2019,  I decided to enter back into the workforce to assist the addicted population.

The overdoses were astounding and I wanted to help.  I consider myself  to be an advocate for the addicted population. My compassion, resilience, empathy, wisdom, knowledge, experience and  love I have for this forgotten population goes beyond words. I consider what I do for the addicted population as a calling versus a “career,” because I too was once an “addict and alcoholic.” Today I am 45.5 years alcohol and substance free.

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Ben Lemmon LCDC III

Hello, my name is Ben Lemmon, and I’m the Vice President and Clinical Director at Ohio Community Health Recovery Centers. I’ve been working in the addiction and mental health field since 2013 and decided to enter the field after overcoming my own challenges with addiction.

When I first meet a client, I always explain to them that the reason we are meeting is because they are not capable of obtaining or maintaining sobriety, and my goal is to create a person that can maintain sobriety. I believe a person’s personality is made up of their thoughts, feelings and actions and my job is to help clients identify the thoughts, feelings and actions that have them disconnected from recovery and provide them with the tools to live a healthy and happy life. Connect with Ben on LinkedIn